| Identification | Back Directory | [Name]
7H-Pyrrolo[2,3-d]pyrimidine-6-carboxylic acid, 7-cyclopentyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]- | [CAS]
2762182-61-4 | [Synonyms]
Ribociclib impurity-1 (Aacid impurity)
7H-Pyrrolo[2,3-d]pyrimidine-6-carboxylic acid, 7-cyclopentyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-
(7-Cyclopentyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid Dihydrochloride) | [Molecular Formula]
C21H25N7O2 | [MOL File]
2762182-61-4.mol | [Molecular Weight]
407.47 |
| Hazard Information | Back Directory | [Uses]
Ribociclib acetate is a degradation product of Ribociclib (HY-15777) under acid-base hydrolysis conditions. Ribociclib acetate has been predicted to be carcinogenic[1]. | [References]
[1] Sahu AK, et al. Identification and structural characterization of potential degraded impurities of ribociclib by time of flight -tandem mass spectrometry, and their toxicity prediction. J Pharm Biomed Anal. 2021 Apr 15;197:113933. DOI:10.1016/j.jpba.2021.113933 |
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