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2763252-25-9

2763252-25-9 Structure

2763252-25-9 Structure
IdentificationBack Directory
[Name]

β-D-Glucopyranosiduronic acid, 2-[[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]acetyl]amino]-4-[[[[[(1S,9S)-9-ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl]amino]carbonyl]oxy]methyl]phenyl
[CAS]

2763252-25-9
[Synonyms]

β-D-Glucopyranosiduronic acid, 2-[[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]acetyl]amino]-4-[[[[[(1S,9S)-9-ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl]amino]carbonyl]oxy]methyl]phenyl
[Molecular Formula]

C47H45FN6O17
[MOL File]

2763252-25-9.mol
[Molecular Weight]

984.89
Chemical PropertiesBack Directory
[density ]

1.69±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

2.77±0.70(Predicted)
[color ]

Light yellow to green yellow
Hazard InformationBack Directory
[Uses]

Mal-Gly-PAB-Exatecan-D-glucuronic acid can be used for Antibody-Drug Conjugates (ADCs) synthesis. Mal-Gly-PAB-Exatecan-D-glucuronic acid can be used for research of tumor research and diagnosis[1].
[IC 50]

Camptothecins
[References]

[1] Anderl Jan, et al. Anti-CEACAM5 antibodies and conjugates and uses thereof. World Intellectual Property Organization, WO2022048883 A1. 2022-03-10.
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