| Identification | Back Directory | [Name]
2,4(1H,3H)-Pyrimidinedione, 5-[6-chloro-5-[(1R,2R)-2-phenylcyclopropyl]-3-pyridazinyl]- | [CAS]
2763710-08-1 | [Synonyms]
CD73-IN-8
2,4(1H,3H)-Pyrimidinedione, 5-[6-chloro-5-[(1R,2R)-2-phenylcyclopropyl]-3-pyridazinyl]- | [Molecular Formula]
C17H13ClN4O2 | [MOL File]
2763710-08-1.mol | [Molecular Weight]
340.76 |
| Hazard Information | Back Directory | [Uses]
CD73-IN-8 is a potent inhibitor of CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73-IN-8 be used for preparing a medicament for tumor-related diseases (extracted from patent WO2022052886A1, compound 57)[1]. | [References]
[1] Hao Wu, et al. Cd73 inhibitor and application thereof in medicine. Patent WO2022052886A1. |
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