ChemicalBook--->CAS DataBase List--->2763827-10-5

2763827-10-5

Request For Quotation

Directory

Chemical Properties

Hazard Information

2763827-10-5 Structure

2763827-10-5 Structure

Identification	Back Directory
[Name] Thalidomide-NH-amido-C2-NH2
[CAS] 2763827-10-5
[Synonyms] Thalidomide-NH-amido-C2-NH2
[Molecular Formula] C17H19N5O5
[MOL File] 2763827-10-5.mol
[Molecular Weight] 373.36

Chemical Properties	Back Directory
[Boiling point ] 775.700±60.00 °C(Press: 760.00 Torr)(predicted)
[density ] 1.492±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[pka] 10.733±0.40(predicted)

Hazard Information	Back Directory
[Uses] Thalidomide-NH-amido-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
[IC 50] Cereblon
[References] [1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.?Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326 [2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277

2763827-10-5 suppliers list

Company Name:	TargetMol
Telephone:	400-821-0310 15002144251
Website:	www.targetmol.cn/

Tags:2763827-10-5 Related Product Information

941678-49-5 474645-27-7 4474-91-3 555-60-2 657-24-9 146986-50-7