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2765264-50-2

2765264-50-2 Structure

2765264-50-2 Structure
IdentificationBack Directory
[Name]

INDEX NAME NOT YET ASSIGNED
[CAS]

2765264-50-2
[Synonyms]

JNJ-6204
2-(5-fluoropyridin-2-yl)-6,6-bis(methyl-d3)-3-(1H-pyrazolo[3,4-b]pyridin-4-yl)-6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazine
[Molecular Formula]

C19H17FN6O
[MOL File]

2765264-50-2.mol
[Molecular Weight]

364.38
Chemical PropertiesBack Directory
[Boiling point ]

580.491±50.00 °C(Press: 760.00 Torr)(predicted)
[density ]

1.499±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
Hazard InformationBack Directory
[Uses]

JNJ-6204 is a dual inhibitor for CSNK1D (Casein Kinase 1 Delta) and CSNK1E (Casein Kinase 1 Epsilon) (CSNK1D IC50=2.3 nM; CSNK1E IC50=137 nM). JNJ-6204 shows good brain exposure[1][2].
[References]

[1] Terry Patrick LEBOLD, et al. Casein kinase 1 delta modulators. WO2022058920A1.
[2] https://www.sgc-ffm.uni-frankfurt.de/#!specificprobeoverview/JNJ-6204
Spectrum DetailBack Directory
[Spectrum Detail]

JNJ-6204(2765264-50-2)1HNMR
2765264-50-2 suppliers list
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