| Identification | Back Directory | [Name]
Benzamide, 4-(3,6-diazabicyclo[3.1.1]hept-3-yl)-2,6-difluoro-N-(4-methoxy-2-benzothiazolyl)- | [CAS]
2765633-68-7 | [Synonyms]
ALPK1-IN-2
Benzamide, 4-(3,6-diazabicyclo[3.1.1]hept-3-yl)-2,6-difluoro-N-(4-methoxy-2-benzothiazolyl)- | [Molecular Formula]
C20H18F2N4O2S | [MOL File]
2765633-68-7.mol | [Molecular Weight]
416.44 |
| Chemical Properties | Back Directory | [density ]
1.463±0.06 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [form ]
Solid | [pka]
7.49±0.70(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
ALPK1-IN-2 (compound T001) is a potent ALPK1 (alpha-kinase 1) inhibitor, with an IC50 of 95 nM. ALPK1-IN-2 also inhibits NF-κB, with an IC50 of 1.31 μM[1]. | [References]
[1] Danyang Liu, et al. Benzothiazole and quinoline derivatives and their use. WO2022063153A1. |
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