| Identification | Back Directory | [Name]
2,4(1H,3H)-Pyrimidinedione, 5-[4-[(1S,2S)-2-(difluoromethyl)cyclopropyl]imidazo[1,5-b]pyridazin-2-yl]- | [CAS]
2766565-88-0 | [Synonyms]
CD73-IN-9
2,4(1H,3H)-Pyrimidinedione, 5-[4-[(1S,2S)-2-(difluoromethyl)cyclopropyl]imidazo[1,5-b]pyridazin-2-yl]- | [Molecular Formula]
C14H11F2N5O2 | [MOL File]
2766565-88-0.mol | [Molecular Weight]
319.27 |
| Hazard Information | Back Directory | [Uses]
CD73-IN-9 is a potent inhibitor of CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73-IN-9 be used for preparing a medicament for tumor-related diseases (extracted from patent WO2022068929A1, compound 2)[1]. | [References]
[1] Xuejun Zhang, et al. Pyrimidinedione compound and use thereof. Patent WO2022068929A1. |
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