| Chemical Properties | Back Directory | [Boiling point ]
395.1±52.0 °C(Predicted) | [density ]
1.34±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 56 mg/mL (200.90 mM);Ethanol: Insoluble | [form ]
Solid | [pka]
10.14±0.10(Predicted) | [color ]
Light yellow to brown | [Water Solubility ]
Water: Insoluble |
| Hazard Information | Back Directory | [Uses]
BPTF-IN-BZ1, a BPTF inhibitor, possesses a high potency (Kd = 6.3 nM). | [Biological Activity]
BZ1 (BPTF inhibitor, BPTF-IN-BZ1) is a pyridazinone-based BPTF (Bromodomain PHD Finger Transcription Factor) inhibitor with a high potency (Kd = 6.3 nM) and >350-fold selectivity over BET bromodomains. | [storage]
Store at -20°C | [References]
[1] Zahid H, et al. J Med Chem. 2021 Sep 23;64(18):13902-13917. |
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