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2767204-90-8

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2767204-90-8 Structure

2767204-90-8 Structure

Identification	Back Directory
[Name] Anticancer agent 194
[CAS] 2767204-90-8
[Synonyms] Anticancer agent 194
[Molecular Formula] C12H16ClN3O2
[MOL File] 2767204-90-8.mol
[Molecular Weight] 269.73

Chemical Properties	Back Directory
[Boiling point ] 519.0±50.0 °C(predicted)
[density ] 1.252±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka] 12.99±0.20(predicted)

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[Uses] Anticancer agent 194 (compound 10p) is a ferroptosis and autophagy inducer. Anticancer agent 194 arrests colon cancer cell cycle at G2/M phase, but can't induce cell apoptosis. Anticancer agent 194 independently triggeres cell ferroptosis and autophagy through the massive accumulation of ROS[1].
[References] [1] Tingting Liang, et al. Discovery of novel urea derivatives as ferroptosis and autophagy inducer for human colon cancer treatment. Eur J Med Chem. 2024 Feb 24:268:116277. DOI:10.1016/j.ejmech.2024.116277

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Company Name:	TargetMol Chemicals Inc.
Tel:	15002134094
Website:	https://www.targetmol.cn/

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