| Identification | Back Directory | [Name]
4-(4-Chlorophenyl)-N-[[(2S)-tetrahydro-2-furanyl]methyl]-1-phthalazinamine | [CAS]
2769040-06-2 | [Synonyms]
NLRP3-IN-18
4-(4-Chlorophenyl)-N-[[(2S)-tetrahydro-2-furanyl]methyl]-1-phthalazinamine | [Molecular Formula]
C19H18ClN3O | [MOL File]
2769040-06-2.mol | [Molecular Weight]
339.82 |
| Chemical Properties | Back Directory | [Boiling point ]
571.9±45.0 °C(Predicted) | [density ]
1.294±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [form ]
Solid | [pka]
5.29±0.30(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
NLRP3-IN-18 (compound 13) is a potent NLRP3 inhibitor with an IC50 value of ≤1.0 μM[1]. | [IC 50]
NLRP3: ≤1.0 μM (IC50) | [References]
[1] Stéphane DORICH, et al. Pyridazine compounds for inhibiting nlrp3. WO2022216971A1. |
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