| Chemical Properties | Back Directory | [density ]
1.405±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
10.684±0.40(predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
SB1-G-187, a PROTAC, is a multi-kinase degrader[1]. SB1-G-187 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [References]
[1] Katherine A Donovan, et al. Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development. Cell. 2020 Dec 10;183(6):1714-1731.e10. DOI:10.1016/j.cell.2020.10.038 |
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