| Identification | Back Directory | [Name]
N-[2-[[4-[[4-(2,6-Dimethylphenoxy)-2-pyrimidinyl]amino]-1-piperidinyl]carbonyl]-1H-indol-5-yl]methanesulfonamide | [CAS]
2771211-71-1 | [Synonyms]
HIV-1 inhibitor-54
N-[2-[[4-[[4-(2,6-Dimethylphenoxy)-2-pyrimidinyl]amino]-1-piperidinyl]carbonyl]-1H-indol-5-yl]methanesulfonamide | [Molecular Formula]
C27H30N6O4S | [MOL File]
2771211-71-1.mol | [Molecular Weight]
534.63 |
| Chemical Properties | Back Directory | [Boiling point ]
782.1±70.0 °C(Predicted) | [density ]
1.399±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [pka]
9.04±0.30(Predicted) |
| Hazard Information | Back Directory | [Uses]
HIV-1 inhibitor-54 is a potent HIV-1 inhibitor. HIV-1 inhibitor-54 has anti-HIV activity in MT-4 cells against WT HIV-1 (strain IIIB) with an EC50 value of 0.032 μM. HIV-1 inhibitor-54 can be used for the research of virus infection[1]. | [IC 50]
HIV-1 | [References]
[1] Ming W, et al. Hybrids of delavirdine and piperdin-4-yl-aminopyrimidines (DPAPYs) as potent HIV-1 NNRTIs: Design, synthesis and biological activities. Eur J Med Chem. 2023 Feb 15;248:115114. DOI:10.1016/j.ejmech.2023.115114 |
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