| Identification | Back Directory | [Name]
1-Piperazineacetamide, 4-[2-chloro-4-(1-piperidinylcarbonyl)phenyl]-N-(2-ethoxyphenyl)- | [CAS]
2776151-36-9 | [Synonyms]
1-Piperazineacetamide, 4-[2-chloro-4-(1-piperidinylcarbonyl)phenyl]-N-(2-ethoxyphenyl)- | [Molecular Formula]
C26H33ClN4O3 | [MOL File]
2776151-36-9.mol | [Molecular Weight]
485.02 |
| Chemical Properties | Back Directory | [Boiling point ]
693.3±55.0 °C(predicted) | [density ]
1.247±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
14.02±0.70(predicted) |
| Hazard Information | Back Directory | [Uses]
L687 is a potent activator of TRPC3/C6/C7 that can induce cellular uptake of oligonucleotides[1]. | [IC 50]
TRPC3; TRPC6; TRPC7 | [References]
[1] Hiroto Kohashi, et al. A novel transient receptor potential C3/C6 selective activator induces the cellular uptake of antisense oligonucleotides. Nucleic Acids Res. 2024 May 22;52(9):4784-4798. DOI:10.1093/nar/gkae245 |
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