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279230-20-5

279230-20-5 Structure

279230-20-5 Structure
IdentificationBack Directory
[Name]

ethyl 3-methyl-4-(3-(pyridin-3-ylmethylamino)propoxy)benzofuran-2-carboxylate
[CAS]

279230-20-5
[Synonyms]

RO094609
RO-094609
RO09-4609
RO 094609
RO 09-4609
RO-09-4609
RO094609,RO 09 4609
ethyl 3-methyl-4-(3-(pyridin-3-ylmethylamino)propoxy)benzofuran-2-carboxylate
2-Benzofurancarboxylic acid, 3-methyl-4-[3-[(3-pyridinylmethyl)amino]propoxy]-, ethyl ester
[Molecular Formula]

C21H24N2O4
[MDL Number]

MFCD29053217
[MOL File]

279230-20-5.mol
[Molecular Weight]

368.43
Chemical PropertiesBack Directory
[Boiling point ]

531.7±50.0 °C(Predicted)
[density ]

1.176±0.06 g/cm3(Predicted)
[pka]

8.51±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

RO-09-4609 exhibits antimicrobial activity, that inhibits Candida albicans, Trypanosoma brucei and Plasmodium vivax through inhibition of N-myristoyl transferase[1].
[References]

[1] Jacobs L, et al., Synthesis of five libraries of 6,5-fused heterocycles to establish the importance of the heterocyclic core for antiplasmodial activity. Bioorg Med Chem. 2018 Nov 15;26(21):5730-5741. DOI:10.1016/j.bmc.2018.10.029
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