| Hazard Information | Back Directory | [Uses]
Azido-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG10-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [IC 50]
PEGs; Alkyl/ether | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
|
| Company Name: |
Xinyanpomei
|
| Tel: |
15850660754 |
| Website: |
http://www.xinyanpomei.com |
| Company Name: |
Biomatrik Inc.
|
| Tel: |
0573-82623377 18967387295 |
| Website: |
www.biomatrik.cn |
|