| Identification | Back Directory | [Name]
4-fluoro-N-[2-(1H-indol-3-yl)ethyl]benzamide | [CAS]
2803-63-6 | [Synonyms]
Z26395438
4-fluoro-N-[2-(1H-indol-3-yl)ethyl]benzamide
Benzamide, 4-fluoro-N-[2-(1H-indol-3-yl)ethyl]- | [Molecular Formula]
C17H15FN2O | [MOL File]
2803-63-6.mol | [Molecular Weight]
282.31 |
| Chemical Properties | Back Directory | [Melting point ]
144-145 °C | [Boiling point ]
532.5±40.0 °C(Predicted) | [density ]
1.262±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
14.75±0.46(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
Z26395438 (compound 1) is a potent Sirtuin-1 inhibitor, with an IC50 value of 1.6 μM[1]. | [References]
[1] Gryniukova A, et al. AI-Powered Virtual Screening of Large Compound Libraries Leads to the Discovery of Novel Inhibitors of Sirtuin-1. J Med Chem. 2023 Aug 10;66(15):10241-10251. DOI:10.1021/acs.jmedchem.3c00128 |
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