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MSU-43085 is an orally active MmpL3 inhibitor of Mycobacterium tuberculosis (Mtb). MSU-43085 effectively inhibits Mtb in an acute murine tuberculosis infection model. MSU-43085 can be used in tuberculosis research[1]. | [References]
[1] Williams JT, et al. The Mycobacterium tuberculosis MmpL3 inhibitor MSU-43085 is active in a mouse model of infection. Microbiol Spectr. 2024 Jan 11;12(1):e0367723. DOI:10.1128/spectrum.03677-23 |
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