| Identification | Back Directory | [Name]
3-Quinolinecarboxylic acid, 6-butyl-1,4-dihydro-4-oxo-7-(2-phenoxyethoxy)-, methyl ester | [CAS]
28130-28-1 | [Synonyms]
780
ICI56
ICI-56
ICI 56
ICI56780
ICI-56780
ICI 56780
3-Quinolinecarboxylic acid, 6-butyl-1,4-dihydro-4-oxo-7-(2-phenoxyethoxy)-, methyl ester | [Molecular Formula]
C23H25NO5 | [MOL File]
28130-28-1.mol | [Molecular Weight]
395.45 |
| Hazard Information | Back Directory | [Description]
ICI-56780 is a antimalarial agent, displaying blood schizonticidal activity against P.berghei. | [Uses]
ICI 56780 is an antimalarial agent, that exhibits etiological prevention and blood schizonticidal activity in rodent malaria models. ICI 56780 develops parasite resistance in P. berghei infected mice[1]. | [References]
[1] Cross RM, et al., Synthesis, antimalarial activity, and structure-activity relationship of 7-(2-phenoxyethoxy)-4(1H)-quinolones. J Med Chem. 2011 Dec 22;54(24):8321-7. DOI:10.1021/jm200718m |
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