| Identification | Back Directory | [Name]
Benzamide, 5-(3-azetidinylamino)-N-[(1R)-1-[3-[5-[(cyclopentylamino)methyl]-2-thienyl]phenyl]ethyl]-2-methyl- | [CAS]
2817810-96-9 | [Synonyms]
Benzamide, 5-(3-azetidinylamino)-N-[(1R)-1-[3-[5-[(cyclopentylamino)methyl]-2-thienyl]phenyl]ethyl]-2-methyl- | [Molecular Formula]
C29H36N4OS | [MOL File]
2817810-96-9.mol | [Molecular Weight]
488.69 |
| Hazard Information | Back Directory | [Uses]
SARS-CoV-2-IN-95 (Compound 10) is an inhibitor for SARS-CoV-2 PLpro with an IC50 of 0.39 μM. SARS-CoV-2-IN-95 exhibits antiviral activity in mouse SARS-CoV-2-infected model[1]. | [References]
[1] Velma GR, et al., Non-Covalent Inhibitors of SARS-CoV-2 Papain-Like Protease (PLpro): In Vitro and In Vivo Antiviral Activity. J Med Chem. 2024 Aug 5. DOI:10.1021/acs.jmedchem.4c00378 |
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