| Identification | Back Directory | [Name]
Benzamide, 5-(3-azetidinylamino)-N-[(1R)-1-[3-[5-[[[(1S,3R)-3-hydroxycyclopentyl]amino]methyl]-2-thienyl]phenyl]ethyl]-2-methyl- | [CAS]
2817811-16-6 | [Synonyms]
Benzamide, 5-(3-azetidinylamino)-N-[(1R)-1-[3-[5-[[[(1S,3R)-3-hydroxycyclopentyl]amino]methyl]-2-thienyl]phenyl]ethyl]-2-methyl- | [Molecular Formula]
C29H36N4O2S | [MOL File]
2817811-16-6.mol | [Molecular Weight]
504.69 |
| Chemical Properties | Back Directory | [Boiling point ]
704.2±60.0 °C(Predicted) | [density ]
1.26±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
14.32±0.46(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
XR8-89 is a potent papain-like protease (PLpro) inhibitor with an IC50 value of 0.1 μM. XR8-89 induces conformational changes in SARS-COV-2 papain-like protease, inhibiting SARS-CoV-2 replication. XR8-89 can be used for SARS-CoV-2 research[1]. | [References]
[1] Ferreira GM, et, al. Inhibitor induced conformational changes in SARS-COV-2 papain-like protease. Sci Rep. 2022 Jul 8;12(1):11585. DOI:10.1038/s41598-022-15181-y |
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