| Identification | Back Directory | [Name]
LRAT-IN-1 | [CAS]
2820064-05-7 | [Synonyms]
LRAT-IN-1
Benzenecarboximidamide, 3-[2-[(dodecylsulfonyl)amino]-3-[4-(methylsulfonyl)-1-piperazinyl]-3-oxopropyl]- | [Molecular Formula]
C27H47N5O5S2 | [MOL File]
2820064-05-7.mol | [Molecular Weight]
585.83 |
| Hazard Information | Back Directory | [Uses]
LRAT-IN-1 (compound 1) is a retinol acyltransferase (LRAT) inhibitor (IC50=21.1 μM). LRAT-IN-1 provides anti-aging effects by inhibiting the esterification of retinol to form retinol esters, increasing the available retinol in the skin. Research on LRAT-IN-1 as an anti-aging ingredient in cosmetics[1]. | [References]
[1] Imfeld, et al. "Boosting of retinol activity using novel lecithin: Retinol acyltransferase inhibitors." International Journal of Cosmetic Science 46.4 (2024): 544-552. DOI:10.1111/ics.12968 |
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