Identification | Back Directory | [Name]
INDEX NAME NOT YET ASSIGNED | [CAS]
2827750-24-1 | [Synonyms]
JYS008 VH032-C1-Boc VH032-CH2-Boc tert-butyl?4-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-4-oxobutanoate | [Molecular Formula]
C30H42N4O6S | [MOL File]
2827750-24-1.mol | [Molecular Weight]
586.75 |
Hazard Information | Back Directory | [Uses]
VH032-CH2-Boc is a Boc-modified VH032 (HY-120217) that serves as a ligand for VHL and recruits von Hippel-Lindau (VHL) proteins. VH032-CH2-Boc will remove the protecting group under acidic conditions and be directly used in PROTAC molecule synthesis. VH032-CH2-Boc is a key intermediate in the synthesis of PROTAC based on VHL ligand. | [IC 50]
VHL |
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