| Identification | Back Directory | [Name]
L-Proline, L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-prolylglycyl-, acetate (1:1) | [CAS]
2828433-33-4 | [Synonyms]
L-Proline, L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-prolylglycyl-, acetate (1:1) | [Molecular Formula]
C37H51N9O10S.C2H4O2 | [MOL File]
2828433-33-4.mol | [Molecular Weight]
873.98 |
| Hazard Information | Back Directory | [Uses]
Semax acetate is a nootropic neuroprotective peptide. Semax acetate can be used in the research of brain stroke[1]. | [References]
[1] Medvedeva EV, et al. The peptide semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia: genome-wide transcriptional analysis. BMC Genomics. 2014 Mar 24;15:228. DOI:10.1186/1471-2164-15-228
[2] Sciacca MFM, et al. Semax, a Synthetic Regulatory Peptide, Affects Copper-Induced Abeta Aggregation and Amyloid Formation in Artificial Membrane Models. ACS Chem Neurosci. 2022 Feb 16;13(4):486-496. DOI:10.1021/acschemneuro.1c00707
[3] Grivennikov IA, et al. Effects of behaviorally active ACTH (4-10) analogue - Semax on rat basal forebrain cholinergic neurons. Restor Neurol Neurosci. 2008;26(1):35-43. PMID:18431004
[4] Shadrina MI, et al. Rapid induction of neurotrophin mRNAs in rat glial cell cultures by Semax, an adrenocorticotropic hormone analog. Neurosci Lett. 2001 Aug 3;308(2):115-8. DOI:10.1016/s0304-3940(01)01994-2 |
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