| Chemical Properties | Back Directory | [Boiling point ]
602.4±55.0 °C(predicted) | [density ]
1.270±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
14.10±0.46(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
HYOU1-IN-1 (Compound 33) is an inhibitor of hypoxia-upregulated protein 1 (HYOU1) with anti-inflammatory activity. HYOU1-IN-1 can be used in research on the regulation of fibroblast activation, chronic inflammation, and fibrotic diseases[1]. | [References]
[1] Papadopoulou D, et al. Discovery of the First-in-Class Inhibitors of Hypoxia Up-Regulated Protein 1 (HYOU1) Suppressing Pathogenic Fibroblast Activation. Angew Chem Int Ed Engl. 2024 Feb 10:e202319157. DOI:10.1002/anie.202319157 |
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