| Identification | Back Directory | [Name]
2,4(1H,3H)-Pyrimidinedione, 1-[5-[[(2S,4R)-1-[(4,4-difluorocyclohexyl)methyl]-2-methyl-4-piperidinyl]methyl]pyrazolo[1,5-a]pyridin-3-yl]dihydro- | [CAS]
2839552-68-8 | [Synonyms]
2,4(1H,3H)-Pyrimidinedione, 1-[5-[[(2S,4R)-1-[(4,4-difluorocyclohexyl)methyl]-2-methyl-4-piperidinyl]methyl]pyrazolo[1,5-a]pyridin-3-yl]dihydro- | [Molecular Formula]
C25H33F2N5O2 | [MOL File]
2839552-68-8.mol | [Molecular Weight]
473.56 |
| Hazard Information | Back Directory | [Uses]
WIZ degrader 1 (Compound 141) is a degrader for widely interspaced zinc finger motifs (WIZ) with an AC50 of 2 nM. WIZ degrader 1 induces the expression of fetal hemoglobin (HbF) with an EC50 of 6 mM. WIZ degrader 1 is used in research of inherited blood disorders[1]. | [References]
[1] BONAZZI S, et al., Pyrazolopyridine Derivatives and Uses thereof. US20240158374A1. |
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