| Chemical Properties | Back Directory | [density ]
1.417±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
11.928±0.30(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Z36-MP5 is an Mi-2β-targeted inhibitor, with IC50 of 0.082 μM. Z36-MP5 can reduce Mi-2β ATPase activity and reactivates ISG transcription. Z36-MP5 can stimulate T-cell-mediated cytotoxicity[1]. | [References]
[1] Cang Li, et al. Mi-2β promotes immune evasion in melanoma by activating EZH2 methylation. Nat Commun. 2024 Mar 9;15(1):2163. DOI:10.1038/s41467-024-46422-5 |
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