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2839660-03-4

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2839660-03-4 Structure

2839660-03-4 Structure
IdentificationBack Directory
[Name]

Z36-MP5
[CAS]

2839660-03-4
[Synonyms]

Z36-MP5
[Molecular Formula]

C22H21N5O2
[MOL File]

2839660-03-4.mol
[Molecular Weight]

387.44
Chemical PropertiesBack Directory
[density ]

1.417±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

11.928±0.30(predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Z36-MP5 is an Mi-2β-targeted inhibitor, with IC50 of 0.082 μM. Z36-MP5 can reduce Mi-2β ATPase activity and reactivates ISG transcription. Z36-MP5 can stimulate T-cell-mediated cytotoxicity[1].
[References]

[1] Cang Li, et al. Mi-2β promotes immune evasion in melanoma by activating EZH2 methylation. Nat Commun. 2024 Mar 9;15(1):2163. DOI:10.1038/s41467-024-46422-5
2839660-03-4 suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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