| Hazard Information | Back Directory | [Description]
Rabelomycin is an angucycline group antibiotic. | [Uses]
Rabelomycin is antibiotic, which exhibits antimicrobial activity against gram positive bacteria. Rabelomycin exhibits inhibitory activity against inducible nitric oxide synthase (iNOS) with an IC50 of 63.9 μM[1][2]. | [IC 50]
iNOS: 63.9 μM (IC50) | [References]
[1] Kharel MK, et al., Enzymatic total synthesis of rabelomycin, an angucycline group antibiotic. Org Lett. 2010 Jun 18;12(12):2814-7. DOI:10.1021/ol1009009
[2] Alvi K A, et al., Identification of inhibitors of inducible nitric oxide synthase from microbial extracts[J]. The Journal of Antibiotics, 2000, 53(5): 496-501. |
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