ChemicalBook--->CAS DataBase List--->2845151-86-0

2845151-86-0

2845151-86-0 Structure

2845151-86-0 Structure
IdentificationBack Directory
[Name]

MEK-IN-6
[CAS]

2845151-86-0
[Synonyms]

MEK-IN-6
[Molecular Formula]

C18H20FN3O4S
[MOL File]

2845151-86-0.mol
[Molecular Weight]

393.43
Chemical PropertiesBack Directory
[Boiling point ]

574.455±60.00 °C(Press: 760.00 Torr)(predicted)
[density ]

1.451±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

14.335±0.10(predicted)
[color ]

White to light yellow
Hazard InformationBack Directory
[Uses]

MEK-IN-6 (Example 69) is a MEK inhibitor. MEK-IN-6 inhibits ERK1/2 (Thr202/Tyr204) phosphorylation in A375 cells (IC50: 2 nM). MEK-IN-6 can be used for research of cancer[1].
[IC 50]

MEK
[References]

[1] Shelley Allen, et al. 3,4-dihydro-2,7-naphthyridine-1,6(2h,7h)-diones as mek inhibitors. Patent. WO2022208391.
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