| Identification | Back Directory | [Name]
10-formyldihydrofolate | [CAS]
28459-40-7 | [Synonyms]
C20H21N7O7
10-ForMyl-7
Folic acid IMpurity F
Folinic Acid IMpurity F
10-formyldihydrofolic acid
Folinic Acid EP Impurity F
Levofolinate EP Impurity F
Impurity F of Calcium Levofolinate
10-Formyl-7,8-dihydro Folic Acid Disodium Salt
10-ForMyl-7,8-dihydro Folic Acid (>85%) DisodiuM Salt
L-Glutamic acid,N-[4-[[(2-amino-3,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]formylamino]benzoyl]- | [Molecular Formula]
C20H21N7O7 | [MOL File]
28459-40-7.mol | [Molecular Weight]
471.43 |
| Chemical Properties | Back Directory | [density ]
1.67±0.1 g/cm3(Predicted) | [solubility ]
Aqueous Acid (Slightly), Aqueous Base (Slightly) | [form ]
Solid | [pka]
3.38±0.10(Predicted) | [color ]
Orange to Very Dark Brown | [Stability:]
Hygroscopic, Temperature Sensitive | [InChIKey]
UXFQDXABPXWSTK-VHLFKADZNA-N | [SMILES]
O=C1N=C(N)NC2NCC(CN(C3C=CC(C(=O)N[C@H](C(=O)O)CCC(=O)O)=CC=3)C=O)=NC1=2 |&1:19,r| |
| Hazard Information | Back Directory | [Uses]
10-Formyl-7,8-dihydrofolic acid is a novel folate found in methotrexate-treated cells. 10-Formyldihydrofolate (H2folate) has not been found as a component of intracellular folates in normal tissues but has been identified in the cytosol of methotrexate (MTX)-treated MCF-7 breast cancer cells and normal human myeloid precursor cells. | [Definition]
ChEBI:10-formyldihydrofolic acid is the 10-formyl derivative of dihydrofolic acid. It is a conjugate acid of a 10-formyldihydrofolate(2-). |
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