| Chemical Properties | Back Directory | [Boiling point ]
611.356±55.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.397±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
6.658±0.20(predicted) |
| Hazard Information | Back Directory | [Uses]
HSD17B13-IN-94 (Compound 12) is an effective inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for Estradiol (HY-B0141). HSD17B13-IN-94 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD, NASH, or drug-induced liver injury (DILI)[1]. | [References]
[1] Joshua Odingo, et al. Thiazole/isothiazole hsd17b13 inhibitors and uses thereof. WIPO (PCT). WO2022216627A1. 2022-10-13 |
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