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2849338-46-9

2849338-46-9 Structure

2849338-46-9 Structure
IdentificationBack Directory
[Name]

HSD17B13-IN-99
[CAS]

2849338-46-9
[Synonyms]

HSD17B13-IN-99
[Molecular Formula]

C24H19F3N4O4
[MOL File]

2849338-46-9.mol
[Molecular Weight]

484.43
Chemical PropertiesBack Directory
[density ]

1.42±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka]

10.50±0.20(predicted)
Hazard InformationBack Directory
[Uses]

HSD17B13-IN-99 (Compound 6) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of < 0.1 μM for estradiol. HSD17B13-IN-99 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].
[References]

[1] Joshua Odingo, et al. Hydroxypyridine hsd17b13 inhibitors and uses thereof. U.S., WO2022216626. 2022-10-13.
2849338-46-9 suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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