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2861994-92-3

2861994-92-3 Structure

2861994-92-3 Structure
IdentificationBack Directory
[Name]

2-[5-(4-Butylphenyl)-2-furanyl]-6-nitro-4-quinolinecarboxylic acid
[CAS]

2861994-92-3
[Synonyms]

2-[5-(4-Butylphenyl)-2-furanyl]-6-nitro-4-quinolinecarboxylic acid
[Molecular Formula]

C24H20N2O5
[MOL File]

2861994-92-3.mol
[Molecular Weight]

416.43
Chemical PropertiesBack Directory
[Boiling point ]

610.3±55.0 °C(Predicted)
[density ]

1.299±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
[pka]

2.25±0.61(Predicted)
Hazard InformationBack Directory
[Uses]

eIF4A3-IN-4 is a novel eIF4A inhibitor with an IC50 value of 8.6 μM.
[IC 50]

eIF4
[References]

[1] Zerio CJ, et al. Discovery of an eIF4A Inhibitor with a Novel Mechanism of Action. J Med Chem. 2021 Nov 11;64(21):15727-15746. DOI:10.1021/acs.jmedchem.1c01014
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