| Identification | Back Directory | [Name]
N-[2-[2-[4-[(4-Chlorobenzyl)oxy]phenoxy]ethoxy]ethyl]cyclohexanamine | [CAS]
2864407-22-5 | [Synonyms]
N-[2-[2-[4-[(4-Chlorobenzyl)oxy]phenoxy]ethoxy]ethyl]cyclohexanamine | [Molecular Formula]
C23H30ClNO3 | [MOL File]
2864407-22-5.mol | [Molecular Weight]
403.94 |
| Chemical Properties | Back Directory | [Boiling point ]
540.892±45.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.161±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
9.339±0.20(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
FOXM1-IN-1 is a potent FOXM1 inhibitor with an IC50 value of 2.65 μM. FOXM1-IN-1 shows antiproliferative activity. FOXM1-IN-1 decreases the the expression of FOXM1, PLK1, CDC25B protein[1]. | [References]
[1] Gao Y, et al. Synthesis and antineoplastic activity of ethylene glycol phenyl aminoethyl ether derivatives as FOXM1 inhibitors. Eur J Med Chem. 2022 Dec 15;244:114877. DOI:10.1016/j.ejmech.2022.114877 |
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