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287194-38-1

287194-38-1 Structure

287194-38-1 Structure
IdentificationBack Directory
[Name]

Cis(+/-)-2-hydroxy-N-(2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl)benzaMide
[CAS]

287194-38-1
[Synonyms]

rel-DHMEQ
DHMEQ (racemate)
TRANS-2-HYDROXY-N-(2-HYDROXY-5-OXO-7-OXABICYCLO[4.1.0]HEPT-3-EN-3-YL)BENZAMIDE
2-hydroxy-N-[(1S,6R)-2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]benzamide
Cis(+/-)-2-hydroxy-N-(2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl)benzaMide
Benzamide, 2-hydroxy-N-[(1R,2R,6R)-2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-, rel-
[Molecular Formula]

C13H11NO5
[MDL Number]

MFCD12965045
[MOL File]

287194-38-1.mol
[Molecular Weight]

261.23
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : ≥ 32 mg/mL (122.50 mM)
[form ]

powder
[color ]

white to beige
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501
Hazard InformationBack Directory
[Biological Activity]

Potentselectiveand irreversible inhibitor of NF-KB th at covalently binds to a cysteine residue.



DHMEQ is a potentselectiveand irreversible inhibitor of NF-KB th at covalently binds to a cysteine residue. It inhibits inflammatory cytokine expression in mice models. DHMEQ is a potent and non/low toxic in vivo anti-inflammatory agent effective in number of animal models.
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