| Identification | Back Directory | [Name]
(5S,6R,7R,8S)-5,6,7,8-Tetrahydro-7,8-dihydroxy-2-[2-(3-phenoxyphenyl)ethyl]-6-(2-phenylethoxy)imidazo[1,2-a]pyridine-5-carboxylic acid | [CAS]
2876926-29-1 | [Synonyms]
(5S,6R,7R,8S)-5,6,7,8-Tetrahydro-7,8-dihydroxy-2-[2-(3-phenoxyphenyl)ethyl]-6-(2-phenylethoxy)imidazo[1,2-a]pyridine-5-carboxylic acid | [Molecular Formula]
C30H30N2O6 | [MOL File]
2876926-29-1.mol | [Molecular Weight]
514.57 |
| Hazard Information | Back Directory | [Uses]
HPSE1-IN-1 (compound 16) is a selective inhibitor of Heparanase-1 (HPSE1) with moderate inhibitory activity against exo-β-d-glucuronidase (GUSβ) and glucocerebrosidase (GBA)[1]. | [References]
[1] Imai Y et al. Discovery of a novel tetrahydroimidazo [1, 2-a] pyridine-5-carboxylic acid derivative as a potent and selective heparanase-1 inhibitor utilizing an improved synthetic approach[J]. Bioorganic & Medicinal Chemistry Letters, 2023: 129543. |
|
|