| Identification | Back Directory | [Name]
(2R)-4-BENZYL-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}MORPHOLIN-3-ONE | [CAS]
287930-75-0 | [Synonyms]
Fosartan impurity
(R)-2-((R)-1-(3,5-bi
Aprepitant Impurity 29
Aprepitant iMpurity 39
Fosaprepitant Impurity C
(2R)-4-Benzyl-2-{(1R)-1-[3,5-Bis(trifluoromethyl)
3-Morpholinone,2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]eth...
4-benzyl-2-[1-[3, 5-bis (trifluoromethyl)phenyl]ethoxy]morpholin-3-one
(R)-4-benzyl-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)Morpholin-3-one
(R)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one
(2R)-4-benzyl-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)Morpholin-3-one
(2R)-4-BENZYL-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}MORPHOLIN-3-ONE
(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-4-(phenylMethyl)-3-Morpholinone
3-Morpholinone,2-[(1R)-1-[3,5-bis(trifluoroMethyl)phenyl]ethoxy]-4-(phenylMethyl)-, (2R)- | [EINECS(EC#)]
1312995-182-4 | [Molecular Formula]
C21H19F6NO3 | [MDL Number]
MFCD22494935 | [MOL File]
287930-75-0.mol | [Molecular Weight]
447.37 |
| Chemical Properties | Back Directory | [Boiling point ]
457.4±45.0 °C(Predicted) | [density ]
1.37 | [storage temp. ]
2-8°C | [pka]
-2.18±0.40(Predicted) | [InChI]
InChI=1S/C21H19F6NO3/c1-13(15-9-16(20(22,23)24)11-17(10-15)21(25,26)27)31-19-18(29)28(7-8-30-19)12-14-5-3-2-4-6-14/h2-6,9-11,13,19H,7-8,12H2,1H3/t13-,19-/m1/s1 | [InChIKey]
KVPJNHLVRGUYGQ-BFUOFWGJSA-N | [SMILES]
N1(CC2=CC=CC=C2)CCO[C@H](O[C@@H](C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)C)C1=O |
| Hazard Information | Back Directory | [Uses]
(2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-4-(phenylmethyl)-3-morpholinone, is the key 3-(4-Fluorophenyl)morpholine moiety used in the synthesis of NK1 receptor antagonist Aprepitant (A729800). |
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