2890177-94-1

Directory

2890177-94-1 Structure

Hazard Information	Back Directory
[Uses] Efflux pump-IN-3 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. Efflux pump-IN-3 inhibits Nile Red (a known substrate of AcrB) efflux. Efflux pump-IN-3 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model[1].
[in vivo] Efflux pump-IN-3 (compound G10) (128 μg/mL; 72 h) shows no significant and in vivo toxicity against Caenorhabditis elegans^[1].
[References] [1] Guo T, et al. Design and synthesis of benzochromene derivatives as AcrB inhibitors for the reversal of bacterial multidrug resistance. Eur J Med Chem. 2023 Mar 5;249:115148. DOI:10.1016/j.ejmech.2023.115148

2890177-94-1 suppliers list

Tags:2890177-94-1 Related Product Information

HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

Login