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2891706-83-3

2891706-83-3 Structure

2891706-83-3 Structure
IdentificationBack Directory
[Name]

BAY-9683
[CAS]

2891706-83-3
[Synonyms]

BAY-9683
[Molecular Formula]

C25H22ClF3N4O3
[MOL File]

2891706-83-3.mol
[Molecular Weight]

518.92
Chemical PropertiesBack Directory
[Boiling point ]

622.4±55.0 °C(Predicted)
[density ]

1.414±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
[pka]

10.02±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

BAY-9683 is an orally active covalent PPARG inverse agonist. BAY-9683 can be used in the study of diseases with overactive PPARG, such as luminal bladder cancer[1].
[References]

[1] Orsi DL, et al. Discovery and characterization of orally bioavailable 4-chloro-6-fluoroisophthalamides as covalent PPARG inverse-agonists. Bioorg Med Chem. 2023 Jan 15;78:117130. DOI:10.1016/j.bmc.2022.117130
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Company Name: Suzhou Meidi Senuo Pharmaceutical Technology Co., Ltd.  
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