| Identification | Back Directory | [Name]
SELENO-DL-CYSTINE | [CAS]
2897-21-4 | [Synonyms]
SELENO-DL-CYSTINE
d,l-selenocystine
seleno-DL-cysteine
SELENIUM-DL-CYSTINE
3’-diselenodi-dl-alanin
Seleno-DL-cystine powder
Alanine, 3,3'-diselenobis-
rac-3,3'-(Diseleno)bis[(R*)-2-aminopropanoic acid] | [Molecular Formula]
C6H12N2O4Se2 | [MDL Number]
MFCD00151368 | [MOL File]
2897-21-4.mol | [Molecular Weight]
334.09 |
| Chemical Properties | Back Directory | [Melting point ]
214.5°C | [Boiling point ]
133.5°C | [storage temp. ]
-20°C | [form ]
powder | [pka]
1.69±0.10(Predicted) | [color ]
yellow to brown | [InChI]
1S/C6H12N2O4Se2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12) | [InChIKey]
JULROCUWKLNBSN-UHFFFAOYSA-N | [SMILES]
NC(C[Se][Se]CC(N)C(O)=O)C(O)=O |
| Safety Data | Back Directory | [Hazard Codes ]
T,N | [Risk Statements ]
23/25-33-50/53 | [Safety Statements ]
20/21-28-45-60-61 | [RIDADR ]
UN 2811 6.1/PG 3 | [WGK Germany ]
3 | [RTECS ]
AY6031000 | [HazardClass ]
6.1(a) | [PackingGroup ]
II | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 1
STOT RE 2 |
| Hazard Information | Back Directory | [Uses]
Selenocystine is a broad-spectrum anti-cancer agent. Selenocystine induces DNA damage in HepG2 cells, particularly in the form of DNA double strand breaks (DSBs). Selenocystine exhibits great promise as a therapeutic or adjuvant agent targeting DNA repair for cancer treatment[1]. | [Definition]
ChEBI: Selenocystine is a diselenide and a selenoamino acid. It is functionally related to a selenocysteine. | [References]
[1] Eva Ari Wahyuni, et al. Selenocystine induces oxidative-mediated DNA damage via impairing homologous recombination repair of DNA double-strand breaks in human hepatoma cells. Chem Biol Interact. 2022 Sep 25:365:110046. DOI:10.1016/j.cbi.2022.110046 |
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| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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