| Chemical Properties | Back Directory | [Boiling point ]
293.7±40.0 °C(predicted) | [density ]
1.170±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
8.76±0.28(predicted) |
| Hazard Information | Back Directory | [Uses]
SERT-IN-3 (compound 12) is an inhibitor of serotonin transporter (SerT). In pharmacological assays, the IC50 of SERT-IN-3 for SerT was 34.4 nM[1]. | [References]
[1] Mente S, et al. Quantitative structure-activity relationship of phenoxyphenyl-methanamine compounds with 5HT2A, SERT, and hERG activities. Bioorg Med Chem Lett. 2008 Dec 1;18(23):6088-92. DOI:10.1016/j.bmcl.2008.10.028 |
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