| Identification | Back Directory | [Name]
Indolizine, 2-(4-methylphenyl)-1-(phenylseleno)- | [CAS]
2901664-87-5 | [Synonyms]
MeSeI
Indolizine, 2-(4-methylphenyl)-1-(phenylseleno)- | [Molecular Formula]
C21H17NSe | [MOL File]
2901664-87-5.mol | [Molecular Weight]
362.33 |
| Hazard Information | Back Directory | [Uses]
MeSeI exhibits a weak inhibitory activity against monoamine oxidase MAO-A and MAO-B (IC50=198.8 μM). MeSeI regulates dopamine receptor D2 and norepinephrine receptor α2, β1, and exhibits antidepressant-like effect in mice. MeSeI is orally active[1]. | [References]
[1] da Rocha MJ, et al., 1-(Phenylselanyl)-2-(p-tolyl)indolizine: A selenoindolizine with potential antidepressant-like activity in mice mediated by the modulation of dopaminergic and noradrenergic systems. Brain Res. 2024 Jul 1;1834:148904. DOI:10.1016/j.brainres.2024.148904 |
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