| Identification | Back Directory | [Name]
1-Piperazinepropanamide, 4-(4′-cyano-3′-fluoro[1,1′-biphenyl]-4-yl)-N-[4-cyano-3-(trifluoromethyl)phenyl]-α-hydroxy-α-methyl-, (αS)- | [CAS]
2902679-11-0 | [Synonyms]
1-Piperazinepropanamide, 4-(4′-cyano-3′-fluoro[1,1′-biphenyl]-4-yl)-N-[4-cyano-3-(trifluoromethyl)phenyl]-α-hydroxy-α-methyl-, (αS)- | [Molecular Formula]
C29H25F4N5O2 | [MOL File]
2902679-11-0.mol | [Molecular Weight]
551.54 |
| Hazard Information | Back Directory | [Uses]
Androgen receptor degrader-5 (compound 14k) exhibits promising properties, including superior androgen receptor degradation activity and antiproliferative activity[1]. | [References]
[1] Wenqiang Zhang, et al. Discovery of novel biphenyl derivatives as androgen receptor degraders for the treatment of enzalutamide-resistant prostate cancer. Bioorg Chem. 2024 Jul:148:107433. DOI:10.1016/j.bioorg.2024.107433 |
|
|