| Identification | Back Directory | [Name]
Meseclazone | [CAS]
29053-27-8 | [Synonyms]
W-2395
NSC297623
Meseclazone
7-chloro-2-methyl-3,3a-dihydro-2H-[1,2]oxazolo[3,2-b][1,3]benzoxazin-9-one
3,3a-Dihydro-7-chloro-2-methyl-2H,9H-isoxazolo[3,2-b][1,3]benzoxazin-9-one
7-Chloro-3,3a-dihydro-2-methyl-2H,9H-isoxazolo[3,2-b][1,3]benzoxazin-9-one
2H,9H-Isoxazolo[3,2-b][1,3]benzoxazin-9-one, 7-chloro-3,3a-dihydro-2-methyl- | [Molecular Formula]
C11H10ClNO3 | [MDL Number]
MFCD00866061 | [MOL File]
29053-27-8.mol | [Molecular Weight]
239.65 |
| Chemical Properties | Back Directory | [Melting point ]
148°C | [Boiling point ]
131.8°C (rough estimate) | [density ]
1.3213 (rough estimate) | [refractive index ]
1.5800 (estimate) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
-3.18±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
Anti-inflammatory. | [in vivo]
Meseclazone inhibits collagen-induced aggregation 1 and 4 hr after oral administration[1]. Intravenous administration of Meseclazone and other nonsteroidal anti-inflammatory drugs caused a dose-dependent inhibition of bronchoconstriction resulting in the following order of descending potency: isoproterenol congruent to indomethacin greater than fenoprofen greater than tolmetin greater than aspirin greater than naproxen congruent to ibuprofen greater than phenylbutazone greater than diflunisal greater than Meseclazone greater than 5-CSA[2]. | [storage]
Store at -20°C |
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cjbscvictory
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13348960310 13348960310 |
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www.weikeqi-biotech.com/ |
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