| Chemical Properties | Back Directory | [Boiling point ]
749.2±70.0 °C(predicted) | [density ]
1.444±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
9.84±0.50(predicted) | [color ]
Yellow to orange |
| Hazard Information | Back Directory | [Uses]
Anti-inflammatory agent 51 (compound 11d) is an amide/sulfonamide derivative with anti-inflammatory activities. Anti-inflammatory agent 51 inhibits NF-κB activation, has the potential for acute lung injury and ulcerative colitis research[1]. | [in vivo]
Anti-inflammatory agent 51 (compound 11d) improved LPS-induced acute lung injury (ALI) and alleviated DSS-induced ulcerative colitis in mice[1]. | [References]
[1] Pan Chen, et al. Design, synthesis, and bioactivity evaluation of novel amide/sulfonamide derivatives as potential anti-inflammatory agents against acute lung injury and ulcerative colitis. Eur J Med Chem. 2023 Aug 2;259:115706. DOI:10.1016/j.ejmech.2023.115706 |
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