| Identification | Back Directory | [Name]
Benzoic acid, 4-(cyclopropylamino)-3-nitro- | [CAS]
291528-35-3 | [Synonyms]
WAY-622024
GPCRagonist-2
WAY622024,WAY 622024
Benzoic acid, 4-(cyclopropylamino)-3-nitro- | [Molecular Formula]
C10H10N2O4 | [MOL File]
291528-35-3.mol | [Molecular Weight]
222.2 |
| Chemical Properties | Back Directory | [Boiling point ]
433.5±40.0 °C(Predicted) | [density ]
1.558±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
4.23±0.10(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
GPCR agonist-2 (Compound 5j) is a GPCR GPR109b (HM74) agonist, with a pEC50 value of 6.51. GPCR agonist-2 can be used for research of lipid disorders[1]. | [References]
[1] Skinner PJ, et al. 3-Nitro-4-amino benzoic acids and 6-amino nicotinic acids are highly selective agonists of GPR109b. Bioorg Med Chem Lett. 2007 Dec 1;17(23):6619-22. DOI:10.1016/j.bmcl.2007.09.058 |
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