ChemicalBook--->CAS DataBase List--->2915356-76-0

2915356-76-0

2915356-76-0 Structure

2915356-76-0 Structure
IdentificationBack Directory
[Name]

Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA-AEEA]-OH
[CAS]

2915356-76-0
[Synonyms]

Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA-AEEA]-OH, Tirzepatide sidechain
[Molecular Formula]

C66H105N5O16
[MOL File]

2915356-76-0.mol
[Molecular Weight]

1224.57
Chemical PropertiesBack Directory
[Boiling point ]

1225.0±65.0 °C (Predicted)
[density ]

1.121±0.06 g/cm3 (Predicted)
[storage temp. ]

2-8°C, sealed storage, away from moisture
[pka]

3.87±0.21(predicted)
[color ]

yellowish
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P280-P305+P351+P338
Raw materials And Preparation ProductsBack Directory
[Preparation Products]

Tirzepatide
Hazard InformationBack Directory
[Description]

Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA-AEEA]-OH (also known as the Tirzepatide side chain, CAS 2915356-76-0; purity 99%) is a key modified amino acid building block used to introduce a long-acting fatty acid chain into therapeutic peptides such as Tirzepatide. This compound is used in the synthesis of tirzepatide via coupling reactions, either by solid-phase peptide synthesis (SPPS) or solution-phase methods. The C20 fatty acid side chain, AEEA and Glu are sequentially attached to the lysine residue.
[Chemical Properties]

colourless/ yellowish liquid
[Uses]

Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA-AEEA]-OH is used as a pharmaceutical intermediate component. It can be used for the synthesis of Tirzepatide, a dual GIP and GLP-1 receptor agonist and a drug candidate for the treatment of type 2 diabetes.
Spectrum DetailBack Directory
[Spectrum Detail]

Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA-AEEA]-OH(2915356-76-0)1HNMR
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