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2919019-36-4

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2919019-36-4 Structure

2919019-36-4 Structure
IdentificationBack Directory
[Name]

HIV-1 inhibitor-64
[CAS]

2919019-36-4
[Synonyms]

HIV-1 inhibitor-64
Hazard InformationBack Directory
[Uses]

HIV-1 inhibitor-64 (Compound 7c) is a wild-type HIV-1 inhibitor that effectively suppresses the activity of HIV-1 mutants E138K/Q148K and G140S/Q148R with EC50 values of 62.5 nM and 11.3 nM, respectively. HIV-1 inhibitor-64 exhibits antiviral activity and can be used in the research of AIDS[1].
[IC 50]

HIV-1 (WT)
[References]

[1] Mahajan, et al. "N-Substituted Bicyclic Carbamoyl Pyridones: Integrase Strand Transfer Inhibitors that Potently Inhibit Drug-Resistant HIV-1 Integrase Mutants." ACS Infectious Diseases (2024). DOI:10.1021/acsinfecdis.3c00525
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