| Identification | Back Directory | [Name]
1,3,5-Benzenetricarboxamide, N1,N3,N5-tris(4-dodecylhexadecyl)- | [CAS]
2922283-38-1 | [Synonyms]
1,3,5-Benzenetricarboxamide, N1,N3,N5-tris(4-dodecylhexadecyl)- | [Molecular Formula]
C93H177N3O3 | [MOL File]
2922283-38-1.mol | [Molecular Weight]
1385.42 |
| Chemical Properties | Back Directory | [Boiling point ]
1147.6±60.0 °C(Predicted) | [density ]
0.894±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [form ]
Oil | [pka]
14.08±0.46(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide is an analogue of TT3 (HY-148049). TT3 is an ionizable lipid-like materials for mRNA delivery[1][2]. | [References]
[1] Li B, Luo X, Deng B, et al. An Orthogonal Array Optimization of Lipid-like Nanoparticles for mRNA Delivery in Vivo.?Nano Lett. 2015;15(12):8099-8107. DOI:10.1021/acs.nanolett.5b03528
[2] Jiang C, Mei M, Li B, et al. A non-viral CRISPR/Cas9 delivery system for therapeutically targeting HBV DNA and pcsk9 in vivo.?Cell Res. 2017;27(3):440-443. DOI:10.1038/cr.2017.16 |
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