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Polθ-IN-3 (Compound 113) is an orally active inhibitor of Polymerase Theta (Polθ). Polθ-IN-3 has antitumor activity[1]. | [References]
[1] Bingcan Liu, et al. N-(5-substituted-[(l,3,4-thiadiazolyl) or (l,3-thiazolyl)](substituted)carboxamide compounds, pharmaceutical compositions, and methods of preparing the amide compounds and of their use. WO2024069592A1. 2024.04.04. |
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