| Chemical Properties | Back Directory | [Boiling point ]
394.0±42.0 °C(predicted) | [density ]
1.23±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
11.66±0.70(predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
SDH-IN-5 (compound 7d) is a potent succinate dehydrogenase (SDH) inhibitor, with an IC50 of 3.293 μM. SDH-IN-5 is also exhibits antifungal activity, with an EC50 of 0.046 μg/mL against R. solani. SDH-IN-5 could significantly inhibit the growth of R. solani in rice leaves with excellent protective and curative efficacies[1]. | [References]
[1] Luo B, et, al. Design, Synthesis, and Antifungal Activities of Novel Pyrazole-4-carboxamide Derivatives Containing an Ether Group as Potential Succinate Dehydrogenase Inhibitors. J Agric Food Chem. 2023 Jun 21;71(24):9255-9265. DOI:10.1021/acs.jafc.3c00116 |
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